Topics

Diseases, drugs, devices, technologies, guidelines and trials.

Faricimab

Evidence, trials and EU product information for faricimab.

Geographic atrophy

A watchpoint for retinal research, registered trials and regulatory context.

ZEISS

Company-sourced developments in ophthalmic devices and digital workflows.

Premium IOLs

Patient-reported outcomes, lens technology and cataract evidence.

Glaucoma

Guidelines, papers and technology in glaucoma.

Cataract

Cataract surgery, IOLs and outcomes.

EUDAMED

Public European medical-device data and implementation milestones.

Cornea

Corneal evidence and clinical reference sources.

AVD-104

Investigational programme in geographic atrophy.

ELIOS

Evidence relating to excimer laser trabeculostomy.

NCT07705555

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

NCT07567833

Longitudinal Study of Retinal Function in Eyes Treated for Diabetic Macular Edema With Anti-VEGF Agents

NCT06790784

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

NCT06541704

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

NCT07440225

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

NCT07215234

A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

NCT06491914

A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

NCT06370039

Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease

NCT05586152

Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease

NCT07246915

Long-term Safety & Performance of REVISYON SDS100 in Mild to Moderate Cataract: Extension Study (EB-CE-02)

NCT07828821

Screening for Diabetic RETINopathy Using a Non-mydriatic Retinograph Funduscope in Occupational MEDicine

NCT07766473

First in Human Study of BETA-TT8 in wetAge-related Macular Degeneration (wetAMD)

NCT07005323

Progression Suppression and Retinal Regression in VEGF-resistant AMD

NCT00594672

Age-Related Eye Disease Study (AREDS) Follow-Up

NCT05955846

Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic

NCT07419334

Study of ALK-001 on the Progression of Stargardt Disease

NCT07826286

Changes in Intraocular Pressure After Intravitreal Injection

NCT07075718

Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

NCT06373731

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

NCT07592273

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

NCT02246829

Assessment of Early Changes in SD-OCT After Initiation of a Treatment by Intravitreal Aflibercept (EYLEA®)START

NCT07825337

Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular Surgery

NCT07614776

A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

NCT04591483

Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

NCT07824232

Visual Function and Exercise in Glaucoma Patients

NCT07734064

A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions

NCT07821827

Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma

NCT06879301

Effectiveness of Intravitreal Injection of Aflibercept 8 mg in Resistant Diabetic Macular Edema, Retinal Vein Occlusion and Myopic Choroidal Neovascularisation Patients

NCT03135327

Clinical Applications of Advanced Ophthalmic Imaging

NCT05839041

A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

NCT07270133

Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes

NCT02959242

Dresden Glaucoma and Treatment Study (DGTS)

NCT07811726

A Phase 2 Study of NT-101 Topical in Patients With Wet AMD

NCT06319872

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

NCT05300724

An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration

NCT01432847

Cell Collection to Study Eye Diseases

NCT06321302

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

NCT07249216

Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting

NCT07821203

Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery

NCT03016156

Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma

NCT05626114

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

NCT06822738

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

NCT07007065

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

NCT03244072

Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery

NCT07820709

Artificial Intelligence for Staging Glaucoma Severity: A Comparison With an Eye Specialist Using Visual Field Tests

NCT07821450

Blepharoptosis After Repeated Intravitreal Anti-VEGF Injections: A Prospective Study

NCT07662096

A First-In-Human Study of ARO-033 in Adult Participants

NCT07819253

Laser Photocoagulation and Ranibizumab Treatment in Proliferative Diabetic Retinopathy

NCT07354477

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

NCT07588100

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

NCT07817615

A Phase I Study of GenSci148 Intravitreal Injection for Neovascular Age-related Macular Degeneration, Diabetic Macular Edema and Retinal Vein Occlusion

NCT07816887

Evaluation of Vitreous Modifications After Cataract Surgery

NCT07816692

iDose TR Administration in an Office-Based Surgery Setting

NCT06635148

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT04567303

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

NCT06925477

Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCT

NCT07816289

Phase 3 Study of Intravitreal OLN324 in Adults With Neovascular (Wet) Age-related Macular Degeneration (nAMD) (OLN324-CP-05)

NCT06213038

A Clinical Study Evaluating the Safety and Efficacy of SKG0106 in Patients With Neovascular Age-related Macular Degeneration (nAMD)

NCT06970665

A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration

NCT07770685

A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage

NCT04663750

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER).

NCT06164743

Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery

NCT07816315

Phase 3 Study of Intravitreal OLN324 in Adults With Neovascular (Wet) Age-related Macular Degeneration (nAMD) (OLN324-CP-04)

NCT07808333

Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)

NCT07099079

Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery

NCT07798375

A Study to Evaluate the Efficacy and Safety of VIS-101 in Participants With Neovascular Age-Related Macular Degeneration

NCT07394257

Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis

NCT07812090

A Randomized, Phase 2 Study of Oral BGE-102 in Participants With Center-Involved Diabetic Macular Edema

NCT07237555

CVL Risk After Severe Glaucoma Surgery

NCT07762053

Clinical Investigation of Eye C Better's Photobionic Intraocular Pressure Biomonitor Tonometer

NCT06659445

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

NCT05984927

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

NCT07441642

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

NCT07804277

Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT)

NCT06825702

Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema

NCT07809022

Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery

NCT06960629

The Effect of ROCK Inhibitors on Corneas of Patients With Glaucoma and Pseudophakic Bullous Keratopathy (PBK)

NCT01957267

Functional and Structural Imaging for Glaucoma

NCT05310422

Safety Study of Tivanisiran to Treat Dry Eye

NCT03811561

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

NCT06969586

The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy

NCT07755748

Glaucoma Screening to Enhance At-Risk Californians' Health - Survey Response Incentives

NCT01878045

Mechanisms of Diabetic Kidney Disease in American Indians

NCT03225131

Dark Adaptation in Participants With Age-Related Macular Degeneration

NCT01496625

National Eye Institute Biorepository for Retinal Diseases

NCT04697095

Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Explants

NCT07481500

Speculum-Free Intravitreal Injection Using Cotton-Tipped Applicator Retraction: Pain, Procedure Time, Patient Satisfaction, and Safety

NCT07807969

An Open-label Extension Study of the Long-Term Safety of Vonaprument (ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)

NCT07668193

GlaukomAI: Clinical Validation of an AI System for Early Glaucoma Screening

NCT07452042

Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract Surgery

NCT07205887

A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

NCT07554690

Photobiomodulation Laser for Reticular Pseudodrusen in Age-Related Macular Degeneration

NCT07230184

To Evaluate the Efficacy and Safety of Combination Therapy With B55R1 and B55R2 Compared to B55R1 Monotherapy in Patients With NPDR